The main factor that may weaken the stability of the roof structure is dampness. On its negative impact it is particularly exposed rafter framing, which deform under impact of water. Therefore is important roof protection against getting in  water into its internal structure.

Typically, investors during the construction of the roof attach great importance both for building materials, as well as careful execution. Unfortunately, later very often they forget about the survey, and any minor defects  commission outsource cheaper and often non-professional roofing companies. This is a big mistake,

Repair holes in metal roof? Depending on the pitch of your roof you should not have to worry about nail holes...I had an old barn with a metal roof at a tenant house I wanted to tear down for F150 Super Crew Water Leak

A very important element that must be considered when the roof is projected, is ventilation, allowing drainage of excess dampness from under the roofing.